The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002167 Q14118 DAG1
DAG1_HUMAN
892 895 KGSRPKNMTPYRSPPPYVPP TP --- Homo sapiens (Human) 895

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Sotgia,2001 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Sotgia,2001 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Sotgia,2001 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06241) FYN_HUMAN PF00017 (SH2)
SH2 domain
149 231 [mitab][xml]

o  Switches



This ELM instance is part of the following 2 switching mechanisms annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence Q14118 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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