The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003876 Q9QZS7-2 Nphs1
NPHN_MOUSE
1177 1181 MAFPGHLYDEVERVYGPPGV TP --- Mus musculus (House mouse) 1242

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Blasutig,2008 support certain InteractionDetection
experimental MI:0113 western blot in vitro Blasutig,2008 support certain ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Blasutig,2008 support certain FeatureDetection
experimental MI:0051 fluorescence technology Blasutig,2008 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P16333) NCK1_HUMAN PF00017 (SH2)
SH2 domain
282 356 1.11/1.49 [mitab][xml]
(O43639) NCK2_HUMAN PF00017 (SH2)
SH2 domain
285 359 0.42/0.5 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org