The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001516 Q01094 E2F1
E2F1_HUMAN
419 427 GLEEGEGIRDLFDCDFGDLT TP --- Homo sapiens (Human) 437

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Helin,1993 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Flemington,1993 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Helin,1993 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01858 (RB_A)
Retinoblastoma-associated protein A domain
373 573 [mitab][xml]
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
645 766 [mitab][xml]

o  Pathways

The sequence Q01094 is implicated in the following 13 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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