The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003113 P45973 CBX5
CBX5_HUMAN
54 75 EKNLDCPELISEFMKKYKKMKE FP 3FDT  
Homo sapiens (Human) 191

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Kaustov,2011 contradict certain InteractionDetection FeatureDetection
experimental MI:0018 two hybrid in vivo Williams,2000 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Nielsen,2001 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Nielsen,2001 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 [mitab][xml]

o  Pathways

Reactome: The sequence P45973 is implicated in the following 0 Pathways:
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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