The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003145 P30279 CCND2
CCND2_HUMAN
2 17 MELLCHEVDPVRRAVRDRNL TP --- Homo sapiens (Human) 289

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Ewen,1993 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Kato,1993 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Ewen,1993 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 [mitab][xml]

o  Pathways

KEGG: The sequence P30279 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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