The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000104 P02751 FN1
FINC_HUMAN
1524 1526 ITVYAVTGRGDSPASSKPIS TP 3VI4  
Homo sapiens (Human) 2386

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Nagae,2012 support certain InteractionDetection FeatureDetection
experimental MI:0030 cross linking study in vivo/in vitro Humphries,2009 support certain InteractionDetection
experimental overlapping binding peptide in vitro Pierschbacher,1984 support certain

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P08648) ITA5_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
326 368 [mitab][xml]
(P08648) ITA5_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
392 428 [mitab][xml]
(P08648) ITA5_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
456 487 [mitab][xml]
(P05556) ITB1_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
34 464 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P02751 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org