The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002212 P35555 FBN1
FBN1_HUMAN
2304 2306 QTKPGICENGRCLNTRGSYT TP --- Homo sapiens (Human) 2871

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental peptide binding to perpetrator in vitro Pfaff,1996 support likely
experimental MI:0663 confocal microscopy in vivo/in vitro Kinsey,2008 support likely InteractionDetection
experimental MI:0054 fluorescence-activated cell sorting in vivo Kinsey,2008 support likely InteractionDetection
experimental MI:0256 rna interference in vivo Kinsey,2008 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06756) ITAV_HUMAN PF08441 (Integrin_alpha2)
Integrin alpha
467 914 [mitab][xml]
(P06756) ITAV_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
[mitab][xml]
(P05556) ITB1_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
34 464 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org