MOD_CDK_1
153
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| Functional site class: | CDK Phosphorylation Site |
| Functional site description: | Site at which CDK's phosphorylate substrates |
|---|---|
| ELMs: | MOD_CDK_1 |
| Description: | Motif in CDK substrates at site of phosphorylation |
| Pattern: | ...([ST])P.[KR] (Probability: 0.0019287) |
| Present in taxons: |
 Eukaryota
|
| Interaction Domain: |
|
|
| Cyclin dependent protein kinases consist of a catalytic kinase domain dependent on a group of proteins called cyclins to become active and phosphorylate substrates. These kinases are essential of cell cycle regulation (eg cdc2/cdk1, cdk2, cdc28). These kinases are generally expressed through out the cell cycle, with the synthesis and degredation of the cyclins during specific phases of the cell cycle. |
2 selected references:
4 GO-Terms:
8 Instances for MOD_CDK_1
(click table headers for sorting)
| Sequence | Start | End | Subsequence | Instance Logic | PDB | Organism |
|---|---|---|---|---|---|---|
 BEM1_YEAST |
48 | 54 | PVRYLSSSSTPVKSQRDSSP | true positive | --- |
Saccharomyces cerevisiae
(Baker"s yeast)
|
|
BEM1_YEAST |
69 | 75 | NRHNSKDITSPEKVIKAKYS | true positive | --- |
Saccharomyces cerevisiae
(Baker"s yeast)
|
|
CDC6_YEAST |
40 | 46 | QFTDVTPESSPEKLQFGSQS | true positive | --- |
Saccharomyces cerevisiae
(Baker"s yeast)
|
|
CDC6_YEAST |
369 | 375 | AQVPLTPTTSPVKKSYPEPQ | true positive | --- |
Saccharomyces cerevisiae
(Baker"s yeast)
|
|
SRC_HUMAN |
72 | 78 | GFNSSDTVTSPQRAGPLAGG | true positive | --- |
Homo sapiens
(Human)
|
|
CDN1B_HUMAN |
184 | 190 | SPNAGSVEQTPKKPGLRRRQ | true positive | --- |
Homo sapiens
(Human)
|
|
MEF2A_HUMAN |
405 | 411 | NISIKSEPISPPRDRMTPSG | true positive | --- |
Homo sapiens
(Human)
|
|
MEF2D_HUMAN |
441 | 447 | HISIKSEPVSPSRERSPAPP | true positive | --- |
Homo sapiens
(Human)
|
Please cite: ELM - the database of eukaryotic linear motifs (PMID:22110040)
ELM data can be downloaded and distributed for non-commercial use according to the ELM Software License Agreement