LIG_PTAP
ELM server details
ELM
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Functional site class:
 PTAP motifs
Functional site description:
 Ebola and HIV display PTAPs in order to facilitate virus budding.
ELM(s): LIG_PTAP
LIG_PTAP description: PTAP alike ligands
Pattern: P[TS]AP
Present in taxon(s): Homo sapiens  
Not represented in taxon(s):

o Abstract

The structural proteins of HIV and Ebola display the PTAP motif (aka \'late domain\') in order to bind the human Tsg101 proteins which facilitate virus budding in the host cell. PTAP alike functional sites might simulate a natural occuring site in the host cell.

o Selected references

o This ELM has been assigned the following Gene Ontology (GO) terms for biological process, cellular component and molecular function.

Biological Process
Cellular Component
Molecular Function

 

o Instances for LIG_PTAP

No instances annotated