| Biochemical
context |
For functional sites, the biochemical
context has several components: the sequence motif, its relation
to the local structure and other domains in the protein as well
as the protein complex it may reside in. |
| Cellular context |
Where and when in the cell a site is functional. |
| Context |
The space and time where a molecular
function takes place. |
| ELM |
1. Eukaryotic Linear Motif.
2. The common pattern of a set of linear (sub)sequences that
can be related to a molecular
function. |
| ELM instance |
An instance of an ELM in a particular polypeptide. |
| Filter |
Method for discriminating between likely positive and negative
ELM predictions; based on context information. |
| Functional
site |
A set of short linear (sub)sequences that can be related to
a molecular function. |
| GO |
Gene Ontology: a controlled vocabulary for describing the
molecular functions, cellular components and biological processes
of genes. See http://www.geneontology.org/ |
| Molecular
context |
see Biochemical context. |
| Molecular
function |
The nature of interaction of a protein with another molecule. |
| Sequence motif |
A recurrent pattern of conserved amino acids. The amino acids
may be absolutely, chemically or sterically conserved. |
| Siteseeing |
The process of annotating ELMs, including developement of
detection methods and evaluation of context information used
to formulate discriminating filters and rules. |
